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Competing interests: None declared.[1] Davis R. Targeting the kids. BMJ 2000;321:354. (5 August.)[2] Letter from Barry M Krivisky of Philip Morris to Philadelphia Chewing Gum Corporation''s president Edward L Fenimore re Marlbro candy cigarettes. 12 Apr 1990. (PM 2062101158-59.)[3] Letter from Jean Bangerter of Philip Morris to Candy Gum SpA''s managing director re imitations of Marlboro and other PM brands. Dec 1990. (PM 2501300795-98.)[4] santadamianahabanos2000rothschild Letter from Elzaburu and De Justo from Philip Morris to Especialidades Nadal SA re Marboro and Chesterfold chocolate cigarettes. Jan 14 1991. (PM 2501300804-06.)[5] Letter from Steven C Parrish of Philip Morris to Confetti Fine Confections re sale of Marlboro bubble gum cigarettes. 22 May 1991. (PM 21162100934-35.)I''m still waiting for my reward
In the present prospective, randomized, double-blind study with 144 smokers, 23.7% of the patients receiving placebo stopped smoking, compared to 55.9% of the patients receiving nortriptyline (p < 0.001). Individuals were considered to have stopped smoking if they claimed total abstinence from cigarette smoking for at least 1 week. Our results were comparable to those of another randomized study by Hurt et al, (16) which included 615 patients who had been treated santadamianahabanos2000rothschild with bupropion. In the sixth week of the study, the abstinence rate was 19% for the group receiving placebo and 44.2% for the group receiving bupropion santadamianahabanos2000rothschild (p < 0.001).Prochazka et al (18) in a randomized, double blind, placebo-controlled study with 214 patients, evaluated the effects of nortriptyline on the rate of ceasing to smoke. santadamianahabanos2000rothschild and santadamianahabanos2000rothschild The success rate for the group that received the active drug was 50%, compared to 32% for the group receiving placebo. Only 12% of the patients had a history of depression, compared to 48% in the population of our study. Despite the difference between the two studies in the methodologies used to obtain this information (in our study, the report on psychiatric treatment for the diagnosis of depression was considered as previous history santadamianahabanos2000rothschild of depression, while in the study by santadamianahabanos2000rothschild Prochazka et al, (18) a structured questionnaire was applied [ie, the diagnostic interview schedule]), the difference between the two populations could explain the different in the rate of success in ceasing to smoke.
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